The EU as a foreign policy actor - should human rights really be promoted in China?

La UE promou les seves normes i principis com els drets humans a tercers països també. en aquest document conceptualitza la UE en el seu poder normatiu i presenta la seva política de drets humans i alguns interpretacions alternatives dels drets humans. La qüestió de si, i en el qual el preu de la UE ha de promoure els drets humans a la Xina, tenint en compte diversos punts de conflicte i si es pot complir amb el seu paper d'un poder normatiu a la llum de diferents restriccions s'examinen. Finalment, és analitza el que això implica per a la realització limitada demanda original de la UE i el que un optimitzat. política de drets humans pot sembla

Low-temperature properties of single-crystal CrB2_{2}

We report the low-temperature properties of $^{11}$B-enriched single-crystal CrB$_{2}$ as prepared from high-purity Cr and B powder by a solid-state reaction and optical float zoning. The electrical resistivity, $\rho_{\rm xx}$, Hall effect, $\rho_{\rm xy}$, and specific heat, $C$, are characteristic of an exchange-enhanced Fermi liquid ground state, which develops a slightly anisotropic spin gap $\Delta \approx 220\,{\rm K}$ below $T_{\rm N}=88\,{\rm K}$. This observation is corroborated by the absence of a Curie dependence in the magnetization for $T\to0$ reported in the literature. Comparison of $C$ with $d\rho_{\rm xx}/dT$, where we infer lattice contributions from measurements of VB$_2$, reveals strong antiferromagnetic spin fluctuations with a characteristic spin fluctuation temperature $T_{\rm sf}\approx 257\,{\rm K}$ in the paramagnetic state, followed by a pronounced second-order mean-field transition at $T_{\rm N}$, and unusual excitations around $\approx T_{\rm N}/2$. The pronounced anisotropy of $\rho_{\rm xx}$ above $T_{\rm N}$ is characteristic of an easy-plane anisotropy of the spin fluctuations consistent with the magnetization. The ratio of the Curie-Weiss to the N$\acute{\rm{e}}$el temperatures, $f=-\Theta_{\rm CW}/T_{\rm N}\approx 8.5$, inferred from the magnetization, implies strong geometric frustration. All physical properties are remarkably invariant under applied magnetic fields up to $14\,\,{\rm T}$, the highest field studied. In contrast to earlier suggestions of local-moment magnetism our study identifies CrB$_{2}$ as a weak itinerant antiferromagnet par excellence with strong geometric frustration.Comment: 15 pages, 9 figure

Humpback Whale (Megaptera novaeangliae) Song on a Subarctic Feeding Ground

Male humpback whales (Megaptera novaeangliae) are known to produce long complex sequences of structured vocalizations called song. Singing behavior has traditionally been associated with low latitude breeding grounds but is increasingly reported outside these areas. This study provides the first report of humpback whale songs in the subarctic waters of Northern Norway using a long-term bottom-moored hydrophone. Data processed included the months January–June 2018 and December 2018–January 2019. Out of 189 days with recordings, humpback whale singing was heard on 79 days. Singing was first detected beginning of January 2018 with a peak in February and was heard until mid-April. No singing activity was found during the summer months and was heard again in December 2018, continuing over January 2019. A total of 131 song sessions, including 35 full sessions, were identified throughout the study period. The longest and shortest complete sessions lasted 815 and 13 min, respectively. The results confirm that singing can be heard over several months in winter and spring on a high latitude feeding ground. This provides additional evidence to the growing literature that singing is not an explicit behavior confined to low latitude breeding grounds. The peak of song occurrence in February appears to coincide with the reproductive cycle of humpback whales. Finally, this study indicates that song occurrence on a subarctic feeding ground likely aids the cultural transmission for the North Atlantic humpback whale population.publishedVersio

Changes in humpback whale song structure and complexity reveal a rapid evolution on a feeding ground in Northern Norway

Singing behaviour by male humpback whales (Megaptera novaeangliae) has traditionally been associated with low-latitude breeding grounds. However, in recent years, this vocal behaviour has been increasingly reported outside these areas. All singers in a given population sing the same version of a song and this song is continually evolving over time with modifications on different levels within the song structure. Tracing changes in whale song will help to undercover the drivers underlying this vocal display and contribute to the understanding of animal culture and its evolution. To determine the progressive changes in songs found on a subarctic feeding ground and migratory stopover, a detailed analysis of humpback whale song recordings from Northern Norway was conducted. Passive acoustic data from the Lofoten-Vesterålen Ocean Observatory (LoVe), collected using a bottom-moored underwater hydrophone, were used from January - April 2018 and January 2019. Two measures of the song structure were examined: (1) sequence similarities using the Levenshtein distance and (2) song complexity using a principal component analysis (PCA). In total, 21 distinct themes were identified which presented highly directional, structural changes over time. Two themes from 2018 reoccurred in 2019, whereas all other themes in 2019 appeared to be evolved versions of 2018 themes. All songs grouped into three general clusters, reflecting the rapid evolution over the study period. With all sampled animals singing the same version of the song, this might indicate that the singers are either from the same breeding population or that song learning occurred before the study period. Song complexity appeared to follow the trend of song progression; songs became more complex as they evolved over the months in 2018 and decreased in complexity between the years, returning to a more simplified song in 2019. The results confirm that humpback whale song exhibits a rapid progression on a shared subarctic feeding ground, with strong potential for song exchange and opportunities for cultural transmission between populations in the North Atlantic

Changes in humpback whale song structure and complexity reveal a rapid evolution on a feeding ground in Northern Norway

Singing behaviour by male humpback whales (Megaptera novaeangliae) has traditionally been associated with low-latitude breeding grounds. However, in recent years, this vocal behaviour has been increasingly reported outside these areas. All singers in a given population sing the same version of a song and this song is continually evolving over time with modifications on different levels within the song structure. Tracing changes in whale song will help to undercover the drivers underlying this vocal display and contribute to the understanding of animal culture and its evolution. To determine the progressive changes in songs found on a subarctic feeding ground and migratory stopover, a detailed analysis of humpback whale song recordings from Northern Norway was conducted. Passive acoustic data from the Lofoten-Vesterålen Ocean Observatory (LoVe), collected using a bottom-moored underwater hydrophone, were used from January - April 2018 and January 2019. Two measures of the song structure were examined: (1) sequence similarities using the Levenshtein distance and (2) song complexity using a principal component analysis (PCA). In total, 21 distinct themes were identified which presented highly directional, structural changes over time. Two themes from 2018 reoccurred in 2019, whereas all other themes in 2019 appeared to be evolved versions of 2018 themes. All songs grouped into three general clusters, reflecting the rapid evolution over the study period. With all sampled animals singing the same version of the song, this might indicate that the singers are either from the same breeding population or that song learning occurred before the study period. Song complexity appeared to follow the trend of song progression; songs became more complex as they evolved over the months in 2018 and decreased in complexity between the years, returning to a more simplified song in 2019. The results confirm that humpback whale song exhibits a rapid progression on a shared subarctic feeding ground, with strong potential for song exchange and opportunities for cultural transmission between populations in the North Atlantic.publishedVersio

Does seismic have an effect on zooplankton? - Field study at Ekofisk with RV Kristine Bonnevie

Toktnr: 2022611Does seismic have an effect on zooplankton? - Field study at Ekofisk with RV Kristine BonneviepublishedVersio

Is there an ideal way to initiate antiplatelet therapy with aspirin? A crossover study on healthy volunteers evaluating different dosing schemes with whole blood aggregometry

<p>Abstract</p> <p>Background</p> <p>Guidelines recommend an early initiation of aspirin treatment in patients with acute cerebral ischemia. Comparative studies on the best starting dose for initiating aspirin therapy to achieve a rapid antiplatelet effect do not exist. This study evaluated the platelet inhibitory effect in healthy volunteers by using three different aspirin loading doses to gain a model for initiating antiplatelet treatment in acute strokes patients.</p> <p>Methods</p> <p>Using whole blood aggregometry, this study with a prospective, uncontrolled, open, crossover design examined 12 healthy volunteers treated with three different aspirin loading doses: intravenous 500 mg aspirin, oral 500 mg aspirin, and a course of 200 mg aspirin on two subsequent days followed by a five-day course of 100 mg aspirin. Aspirin low response was defined as change of impedance exceeding 0 Ω after stimulation with arachidonic acid.</p> <p>Results</p> <p>Sufficient antiplatelet effectiveness was gained within 30 seconds when intravenous 500 mg aspirin was used. The mean time until antiplatelet effect was 74 minutes for 500 mg aspirin taken orally and 662 minutes (11.2 hours) for the dose scheme with 200 mg aspirin with a high inter- and intraindividual variability in those two regimes. Platelet aggregation returned to the baseline range during the wash-out phase within 4 days.</p> <p>Conclusion</p> <p>Our study reveals that the antiplatelet effect differs significantly between the three different aspirin starting dosages with a high inter- and intraindividual variability of antiplatelet response in our healthy volunteers. To ensure an early platelet inhibitory effect in acute stroke patients, it could be advantageous to initiate the therapy with an intravenous loading dose of 500 mg aspirin. However, clinical outcome studies must still define the best way to initiate antiplatelet treatment with aspirin.</p

Intra- and inter-laboratory agreement of the FAM19A4/mir124-2 methylation test: results from an international study

BACKGROUND: HPV-based cervical screening detects women at an increased risk of cervical cancer and precancer. To differentiate among HPV-positive women those with (pre)cancer, triage testing is necessary. The detection of cancer-associated host-cell DNA methylation (FAM19A4 and hsa-mir124-2) in cervical samples has shown valuable as triage test. This multicenter study from 6 collaborating European laboratories and one reference laboratory was set out to determine the intra- and inter-laboratory agreement of FAM19A4/mir124-2 DNA methylation analysis utilizing the QIAsure Methylation Test. METHODS: Agreement analysis for the QIAsure Methylation Test was assessed on high-risk HPV-positive cervical specimens (n = 1680) both at the level of the assay and at the full workflow, including bisulfite conversion. RESULTS: Intra- and inter-laboratory assay agreement were 91.4% (534/584; 95% CI 88.9-93.5; κ = 0.82) and 92.5% (369/399; 95% CI 90.0-94.7; κ = 0.83), respectively. The inter-laboratory workflow (bisulfite conversion and assay combined) agreement was 90.0% (627/697; 95% CI 87.5%-92.0%; κ = 0.76). CONCLUSION: These data show that the QIAsure Methylation Test performs robust and reproducible in different laboratory contexts. These results support the use of the QIAsure Methylation Test for full molecular screening for cervical cancer, including primary HPV testing and triage testing by methylation analysis